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Fmoc-His-Aib-OH is a dipeptide building block used in peptide synthesis, combining Fmoc-protected histidine and Aib (α-aminoisobutyric acid). Aib introduces conformational rigidity, making it valuable for designing helical and stable peptides.
Fmoc-His-Aib-OH is a dipeptide building block used in peptide synthesis, combining Fmoc-protected histidine and Aib (α-aminoisobutyric acid). Aib introduces conformational rigidity, making it valuable for designing helical and stable peptides.
Research & Applications
Ideal for solid-phase peptide synthesis (SPPS)
Enhances proteolytic resistance and structural stability
Used in developing bioactive peptides and peptidomimetics
Product Features
High purity (≥99%)
Fmoc-protected for SPPS compatibility
Fmoc-His-Aib-OH supports advanced research in peptide drug design and structural biology.
Frequently Asked Questions (FAQ)
1. What is Fmoc-His-Aib-OH?
Fmoc-His-Aib-OH is a dipeptide building block commonly utilized in peptide synthesis. It combines Fmoc-protected histidine with α-aminoisobutyric acid (Aib).
2. What role does Aib play in this dipeptide?
Aib (α-aminoisobutyric acid) introduces conformational rigidity into the peptide structure, which is valuable for designing helical and highly stable peptides.
3. What are the main applications of Fmoc-His-Aib-OH?
It is ideal for solid-phase peptide synthesis (SPPS), enhancing proteolytic resistance and structural stability, and is used to develop bioactive peptides and peptidomimetics.
4. What is the purity level of Fmoc-His-Aib-OH?
The product features high purity with a specification of ≥99%.
5. Is Fmoc-His-Aib-OH compatible with Solid-Phase Peptide Synthesis (SPPS)?
Yes, it is Fmoc-protected, ensuring direct compatibility with standard Solid-Phase Peptide Synthesis (SPPS) protocols.
6. How does Fmoc-His-Aib-OH contribute to drug design research?
By offering structural stability and high purity, Fmoc-His-Aib-OH supports advanced research in peptide drug design and structural biology.