Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH is a functionalized amino acid building block designed for targeted drug delivery and bioconjugation. It features an Eic (eicosanoid) moiety for lipid interaction, γ-Glu for targeting, and AEEA spacers for flexibility.
Used in prodrug synthesis, ADC development, and nanocarrier design
Enhances membrane targeting, solubility, and conjugation efficiency
Suitable for SPPS in advanced peptide–drug conjugate research
Fmoc-protected, high purity (≥99%)
Contains cleavable OtBu groups for controlled synthesis
Ideal for precision delivery systems and functional peptide design
It is a specialized building block primarily used in targeted drug delivery, bioconjugation, antibody-drug conjugate (ADC) development, prodrug synthesis, and nanocarrier design.
The structure incorporates an Eic (eicosanoid) moiety for lipid interaction, γ-Glu for cell targeting, and AEEA spacers to improve overall molecular flexibility.
Yes, it features Fmoc protection and cleavable OtBu groups, making it fully compatible with SPPS protocols for advanced peptide-drug conjugate research.
This product is Fmoc-protected and maintained at a high purity standard of ≥99% for precise and reproducible synthesis.
AEEA (aminoethoxyethoxyacetyl) spacers increase hydrophilicity and spatial flexibility, which helps improve membrane targeting, solubility, and overall conjugation efficiency.