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Wholesale Fmoc-Ile-Aib-OH Suppliers, Exporters
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Wholesale Fmoc-Ile-Aib-OH Suppliers, Exporters

Wholesale Fmoc-Ile-Aib-OH Suppliers, Exporters

Fmoc-Ile-Aib-OH is a dipeptide building block used in solid-phase peptide synthesis (SPPS). It combines Fmoc-protected isoleucine with Aib (α-aminoisobutyric acid), a non-natural amino acid that enhances helix stability and protease resistance.
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Product Description

Fmoc-Ile-Aib-OH is a dipeptide building block used in solid-phase peptide synthesis (SPPS). It combines Fmoc-protected isoleucine with Aib (α-aminoisobutyric acid), a non-natural amino acid that enhances helix stability and protease resistance.

Research & Applications

Helical Peptide Design

Ideal for designing stable, helical peptides required for structural and functional biological studies.

Peptidomimetic Development

Widely used in advanced peptidomimetic development and innovative targeted drug design workflows.

Metabolic Stability

Significantly improves conformational rigidity and enhances resistance against metabolic degradation.

Product Features

High purity ≥99%
Fmoc-protected, SPPS-compatible
Fmoc-Ile-Aib-OH is a valuable tool for advanced peptide and therapeutic research.

Frequently Asked Questions

What is Fmoc-Ile-Aib-OH used for?
Fmoc-Ile-Aib-OH is a dipeptide building block primarily utilized in solid-phase peptide synthesis (SPPS) to introduce α-aminoisobutyric acid (Aib) combined with isoleucine into peptide chains for therapeutic research and drug design.
What role does Aib (α-aminoisobutyric acid) play in peptide synthesis?
Aib is a non-natural, sterically hindered amino acid that strongly promotes helical conformations, enhancing the secondary structure stability, conformational rigidity, and enzymatic resistance of synthetic peptides.
What is the purity level of Fmoc-Ile-Aib-OH?
This product features a high purity level of ≥99%, making it ideal for high-precision peptide synthesis and advanced pharmaceutical research applications.
Is Fmoc-Ile-Aib-OH compatible with standard SPPS protocols?
Yes, because it is Fmoc-protected, it integrates seamlessly into conventional Fmoc-based Solid-Phase Peptide Synthesis (SPPS) workflows.
How does this product improve metabolic stability?
The incorporation of the non-natural amino acid Aib restricts backbone flexibility and protects adjacent peptide bonds from enzymatic cleavage by proteases, thus extending metabolic half-life.

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