OEM Other Protected Amino Acids for Disulfide bond Factory, Companies

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OEM Other Protected Amino Acids for Disulfide bond Factory, Companies

NO	Products	CAS No	Application
1	Fmoc-Cys(Mmt)-OH	177582-21-7	Disulfide bond
2	Fmoc-Cys(4-allylbutyrate)-OH	/	Disulfide bond
3	Mpa(Trt)-OH	27144-18-9	End of sequence

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Product Description

Product Specifications & Technical Data

NO	Products	CAS No	Application	Key Quality Indicator
NO	Products	CAS No	Application	Purity	Isomer	Specific impurity	*Max1	Moisture
1	Fmoc-Cys(Acm)-OH	86060-81-3	Disulfide bond	≥99.0%	≤0.1%	≤0.1%	≤0.2%	≤1.0%
2	Fmoc-Cys(Mmt)-OH	177582-21-7	Disulfide bond	≥98.0%	≤0.2%	≤0.3%	≤0.5%	≤1.0%
3	Fmoc-Cys(4-allylbutyrate)-OH	/	Disulfide bond	≥98.0%	≤0.2%	≤0.3%	≤0.5%	≤1.0%
4	Mpa(Trt)-OH	27144-18-9	End of sequence	≥99.5%	/	≤0.1%	≤0.2%	≤1.0%
5	Fmoc-Thr(tBu)-OL	189337-28-8	Octreotide	≥97.0%	≤0.3%	≤0.5%	≤1.0%	≤1.0%
6	Fmoc-D-Arg(pbf)-OH	187618-60-6	Desmopressin	≥99.0%	≤0.2%	≤0.3%	≤0.3%	≤2.0%
7	Fmoc-Gly-Gly-OH	35665-38-4	Bivalirudin	≥99.5%	/	≤0.1%	≤0.2%	≤1.0%
8	Fmoc-Gly-Gly-Gly-OH	170941-79-4	Terlipressin	≥99.5%	/	≤0.1%	≤0.2%	≤1.0%
9	Fmoc-Gly-Gly-Gly-Gly-OH	/	Bivalirudin	≥99.5%	/	≤0.1%	≤0.2%	≤1.0%
10	Fmoc-Gly-Asp(tBu)-OH	/	Bivalirudin	≥99.5%	/	≤0.15%	≤0.2%	≤1.0%
11	Boc-Cys(Trt)-OH	21947-98-8	End of sequence	≥99.0%	≤0.2%	≤0.3%	≤0.3%	≤1.0%
12	Boc-Arg(pbf)-OH	200124-22-7	End of sequence	≥99.0%	≤0.2%	≤0.3%	≤0.3%	≤1.0%
13	Boc-Ala-OH	15761-38-3	End of sequence	≥99.0%	≤0.2%	≤0.3%	≤0.3%	≤1.0%
14	Boc-D-Phe-OH	18942-49-9	End of sequence	≥99.0%	≤0.2%	≤0.3%	≤0.3%	≤1.0%
15	Boc-Gly-OH	4530-20-5	End of sequence	≥99.5%	/	≤0.1%	≤0.2%	≤1.0%
16	Boc-Lys(Boc)-OH.DCHA	15098-69-8	End of sequence	≥99.0%	≤0.2%	≤0.3%	≤0.3%	≤1.0%
17	Boc-Ser(tBu)-OH	7738-22-9	End of sequence	≥99.0%	≤0.2%	≤0.3%	≤0.3%	≤1.0%
18	Boc-Thr(tBu)-OH	13734-40-2	End of sequence	≥99.0%	≤0.2%	≤0.3%	≤0.3%	≤1.0%
19	Boc-D-Ala-OH	7764-95-6	End of sequence	≥99.0%	≤0.2%	≤0.3%	≤0.3%	≤1.0%
20	Boc-Met-OH	2488-15-5	End of sequence	≥99.0%	≤0.2%	≤0.3%	≤0.3%	≤1.0%
21	Boc-Tyr(tBu)-OH	47375-34-8	End of sequence	≥99.0%	≤0.2%	≤0.3%	≤0.3%	≤1.0%
22	Boc-D-Arg(pdf)-OH	187618-60-6	End of sequence	≥99.0%	≤0.2%	≤0.3%	≤0.3%	≤1.0%
23	Boc-Asp(OtBu)-OH.DCHA	1913/12/8	End of sequence	≥99.0%	≤0.2%	≤0.3%	≤0.3%	≤1.0%
24	Fmoc-HomoArg(pbf)-OH	1159680-21-3	Eptifibatide	≥98.5%	≤0.2%	/	≤0.5%	≤2.0%
25	Fmoc-Asp-OtBu	129460-09-9	Thymalfasin	≥99.5%	≤0.1%	≤0.1%	≤0.2%	≤1.0%
26	Fmoc-Tyr(Me)-OH	77128-72-4	Carbetocin	≥98.5%	≤0.2%	≤0.3%	≤0.5%	≤1.0%
27	Fmoc-Orn(Boc)-OH	109425-55-0	Atosiban / Omnipressin / Daptomycin	≥99.5%	≤0.1%	≤0.1%	≤0.2%	≤2.0%
28	Fmoc-D-Tyr(Et)-OH	162502-65-0	Atosiban	≥99.5%	≤0.1%	≤0.1%	≤0.2%	≤1.0%
29	Fmoc-Asp(OAll)-OH	146982-24-3	Melanotan	≥99.0%	≤0.2%	≤0.3%	≤0.3%	≤1.0%
30	Ac-Nle-OH	15891-49-3	Melanotan	≥99.0%	/	≤0.3%	≤0.3%	≤1.0%
31	Fmoc-Nle-OH	77284-32-3	Melanotan / Afamelanotide	≥99.0%	/	≤0.3%	≤0.3%	≤1.0%
32	Ac-Glu(OtBu)-OH	84192-88-1	Argireline / Acetyl octapeptide-3	≥99.0%	≤0.2%	≤0.3%	≤0.3%	≤1.0%
33	Ac-β-Ala-OH·DCHA	/	Acetyl tetrapeptide-5	≥99.0%	/	≤0.3%	≤0.3%	≤1.0%
34	Fmoc-ß-Ala-OH	35737-10-1	Acetyl tetrapeptide-5	≥99.5%	/	≤0.1%	≤0.2%	≤1.0%
35	Fmoc-Hyp(tBu)-OH	122996-47-8	Icatibant	≥98.0%	≤0.2%	≤0.3%	≤0.5%	≤1.0%
36	Fmoc-Thi-OH	130309-35-2	Icatibant	≥98.0%	≤0.2%	≤0.3%	≤0.5%	≤1.0%
37	Fmoc-D-Tic-OH	130309-33-0	Icatibant	≥98.0%	≤0.2%	≤0.3%	≤0.5%	≤1.0%
38	Fmoc-Oic-OH	130309-37-4	Icatibant	≥98.0%	≤0.2%	≤0.3%	≤0.5%	≤1.0%
39	Boc-Sar-OH	13734-36-6	Saralasin	≥98.0%	≤0.2%	≤0.3%	≤0.5%	≤1.0%
40	Fmoc-Sar-OH	77128-70-2	Saralasin	≥98.0%	≤0.2%	≤0.3%	≤0.5%	≤1.0%
41	Fmoc-Tyr(SO3Na)-OH.H2O	106864-37-3	Sincalide	≥98.0%	≤0.2%	≤0.3%	≤0.5%	≤1.0%
42	Fmoc-D-Asp(OtBu)-OH	112883-39-3	Daptomycin	≥98.5%	≤0.2%	≤0.3%	≤0.5%	≤1.0%
43	Ac-Ser(tBu)-OH	77285-09-7	Afamelanotide	≥99.0%	≤0.2%	≤0.3%	≤0.3%	≤1.0%
44	Boc-HomoCys(Trt)-OH	201419-16-1	Depreotide	≥98.0%	≤0.2%	≤0.3%	≤0.5%	≤1.0%
45	Fmoc-HomoCys(Trt)-OH	167015-23-8	Depreotide	≥98.0%	≤0.2%	≤0.3%	≤0.5%	≤1.0%
46	Fmoc-Dab-OH	161420-87-7	Snake venom	≥99.0%	≤0.2%	≤0.3%	≤0.3%	≤1.0%

Note: *Max1 indicates Maximum Unknown Impurity allowed per batch standard.

General Quality Indicators

Acetic Acid

≤ 0.02%

Ethyl Acetate

≤ 0.5%

Alcohol Limit

≤ 0.5%

Max Unknown Impurity

≤ 0.2% (Fmoc-Trp(Boc)-OH ≤ 0.3%)

Frequently Asked Questions (FAQ)

What applications are these amino acid derivatives suitable for?

These Fmoc and Boc protected amino acid derivatives are essential building blocks primarily used in solid-phase peptide synthesis (SPPS) and liquid-phase synthesis for producing therapeutic peptides, active pharmaceutical ingredients (APIs) such as Bivalirudin, Terlipressin, Atosiban, and cosmetic peptides like Argireline.

How are purity and quality indicators tested?

All chemical purity parameters, including enantiomeric isomer limits, specific impurities, and unknown impurities (*Max1), are verified using High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry, ensuring strict adherence to global pharmaceutical standards.

What does the "*Max1" specification column represent?

The *Max1 column specifies the maximum allowable limit for any single unknown impurity present in the product batch, guaranteeing batch-to-batch consistency and minimizing side reactions during peptide chain elongation.

What are the standard residual solvent parameters across all products?

All listed amino acid derivatives follow strict residual solvent limits: Acetic Acid is maintained at ≤ 0.02%, Ethyl Acetate at ≤ 0.5%, and total Alcohol content at ≤ 0.5%.

What are the recommended handling and storage conditions?

To maintain product purity and prevent moisture absorption or degradation, these compounds should be stored in tightly sealed containers at controlled cool temperatures (typically 2°C to 8°C or -20°C for long-term storage) protected from light and humidity.

Can customized purity or moisture specifications be requested?

Yes, tailored quality control parameters—including stricter moisture thresholds, lower isomer limits, or specific salt forms—can be evaluated depending on synthesis requirements and industrial applications.