Industrial Chemical Whitepaper & Global Sourcing Guide

China Oxyquinoline Sulfate Suppliers & Factory

High-Purity 8-Hydroxyquinoline Sulfate (CAS 134-31-6) Manufacturing, cGMP Quality Standards, Global Regulatory Compliance, and B2B Enterprise Supply Chain Integration

99.5%
Minimum Assay HPLC Purity
250K m²
Standard Manufacturing Base
ISO/cGMP
Global Compliance Standard
50+
Countries Export Footprint

1. Executive Technical Briefing: Chemical Profile of Oxyquinoline Sulfate

Oxyquinoline Sulfate (also known as 8-hydroxyquinoline sulfate, bis(8-hydroxyquinolinium) sulfate, CAS No: 134-31-6 or di-8-hydroxyquinoline sulfate) is a versatile heterocyclic aromatic coordination compound. Engineered via precise stoichiometry between 8-hydroxyquinoline base and sulfuric acid, it exhibits exceptional antimicrobial, antifungal, microbicidal, and metal-chelating properties.

In modern chemical manufacturing, China has established itself as the global hub for high-purity Oxyquinoline Sulfate synthesis. Through specialized catalytic crystallization techniques, Chinese chemical plants produce ultra-pure, light-yellow crystalline powder designed to satisfy demanding requirements across agricultural plant protection, cosmetics preservation, industrial biocide processing, and active pharmaceutical ingredient (API) synthesis.

Comprehensive Analytical Specifications (COA Benchmark)

Parameter / Parameter Name Guaranteed Specification Standard Analytical Testing Method
Chemical Formula (C9H7NO)2 · H2SO4 Molecular Structure Validation
CAS Registry Number 134-31-6 / 21454-15-3 (Monohydrate) CAS Standard Index
Appearance Light Yellow Crystalline Powder Visual / Sensory Inspection
Assay (Purity content) ≥ 99.0% (Pharma/Tech Grade Options) HPLC / Potentiometric Titration
Melting Point Range 175°C – 178°C (Decomposition) Capillary Tube Melting Apparatus
Loss on Drying (Moisture) ≤ 0.5% max Gravimetric (105°C for 2 Hours)
Residue on Ignition (Ash) ≤ 0.1% max Muffle Furnace Ashing (600°C)
Heavy Metals (as Pb) ≤ 10 ppm max ICP-MS / Colorimetric Comparison
Solubility in Water Freely soluble in water, sparingly soluble in ethanol Gravimetric Dissolution Method

2. China's Factory Ecosystem & Supply Chain Advantages

Procuring Oxyquinoline Sulfate directly from China chemical manufacturers grants multinational buyers unrivaled economic and logistical advantages. The integrated vertical supply chain within major chemical industrial parks ensures operational resilience, price stability, and scalable bulk availability.

Upstream Raw Material Integration

China produces over 70% of the world's precursor chemicals, including aniline and acrolein derivatives required for 8-hydroxyquinoline synthesis. Direct raw material access isolates factories from global spot price shocks.

Advanced Green Synthesis & Scale

Modern Chinese manufacturing facilities operate continuous automated crystallization reactors. Closed-loop chemical recovery systems dramatically lower energy costs while maintaining zero toxic discharge compliance.

Port Infrastructure & Freight Speed

Proximity to Tier-1 international deep-water ports (Shanghai, Ningbo, Qingdao) ensures seamless container consolidation, immediate Dangerous Goods (DG) packing authorization, and minimal export lead times.

3. Versatile Application Matrix & Localized Industry Scenarios

Because of its strong chelation capability with essential trace metal ions ($Cu^{2+}$, $Fe^{3+}$, $Zn^{2+}$) necessary for micro-organism metabolism, Oxyquinoline Sulfate functions as a broad-spectrum antimicrobial agent across diverse global sectors.

Agricultural Crop Protection & Horticulture

Used widely in Europe, South America, and Asia as a broad-spectrum systemic fungicide and bactericide. It effectively treats soil-borne vascular wilt disease, root rot caused by Fusarium, and bacterial spot in commercial crops, cut flowers, and greenhouses. Its high water solubility allows for easy spray formulation.

Veterinary Formulations & Disinfection

Incorporated into topical antiseptic gels, teat dips for dairy cattle, and wound spray formulations. Oxyquinoline Sulfate effectively suppresses Gram-positive and Gram-negative pathogenic bacteria without causing tissue cytotoxicity or systemic bio-accumulation.

Cosmetics & Personal Care Preservatives

Serves as a robust anti-dandruff additive in medical shampoos, deodorants, and skin lotions. Acts as an antimicrobial booster that enhances secondary preservative systems while inhibiting fungal microflora like Malassezia globosa.

Metal Extraction & Analytical Chemistry

Leveraging its powerful chelating ligand backbone, analytical grade Oxyquinoline Sulfate is deployed in gravimetric determination, photometric analysis of trace metals, and selective extraction of precious/heavy transition metal ions from industrial sludge.

4. Quality Assurance, Regulatory Compliance & Local Support

Navigating international regulatory frameworks requires complete chemical traceability, batch consistency, and transparent safety dossiers. Premier Chinese suppliers maintain full alignment with western regulatory bodies.

EU REACH & Global Registration

Full REACH registration dossiers enable seamless chemical imports into European Union member states. Complete GHS-compliant Safety Data Sheets (SDS) are provided in multiple languages.

cGMP & ISO Certifications

Factories adhere strictly to ISO 9001:2015 Quality Management Systems and ISO 14001:2015 Environmental Management Standards, with specialized cGMP lines for pharmaceutical-grade batches.

Advanced Analytical Validation

Every shipment is accompanied by a Certificate of Analysis (COA) supported by High-Performance Liquid Chromatography (HPLC), Nuclear Magnetic Resonance (NMR), and Heavy Metal ICP-MS testing.

5. Industry Development Trends & Strategic Procurement Guidance

As the global chemical landscape pivots toward bio-compatible preservatives and non-toxic agricultural active agents, Oxyquinoline Sulfate demand is expanding exponentially across developing agricultural and medical markets.

Key Market Growth Drivers & Innovations

  • Shift toward Low-Toxicity Fungicides: Stricter global bans on organochlorine and toxic heavy-metal fungicides boost the adoption of biodegradable metal-chelating agents like Oxyquinoline Sulfate.
  • Micronization & Custom Particle Engineering: Enterprise buyers increasingly demand specific mesh sizes (e.g., 80 mesh to ultra-fine 320 mesh) to enhance liquid dissolution speed in automatic farm spraying setups.
  • Flexible Enterprise OEM/ODM Packaging: Custom packaging options ranging from 25kg UN-approved fiber drums to 500kg super-sacks lined with moisture-barrier aluminum foil protect chemical stability across equatorial sea lanes.

6. Frequently Asked Questions (FAQ) & Technical Guidance

Essential technical answers for international chemical buyers, quality control engineers, and procurement directors.

Q1: What is the primary functional difference between 8-Hydroxyquinoline Base and Oxyquinoline Sulfate?
8-Hydroxyquinoline Base (CAS 148-24-3) is practically insoluble in water, rendering it suitable mainly for solvent-based organic applications. In contrast, Oxyquinoline Sulfate (CAS 134-31-6) is the salt form, which is freely soluble in water. This water solubility is essential for aqueous agricultural sprays, antiseptic washes, and liquid preservative systems.
Q2: How does Oxyquinoline Sulfate function as an antimicrobial biocide?
It acts via dynamic metal-chelation mechanisms. By binding essential divalent and trivalent metallic cations ($Fe^{3+}$, $Cu^{2+}$) required for cellular respiration in bacteria and fungi, it disrupts cell membrane permeability and inhibits metabolic enzymes, preventing microbial reproduction.
Q3: What are the standard packaging and storage requirements for bulk export?
Standard packaging consists of 25kg cardboard/fiber drums with double polyethylene inner bags. It should be stored in a cool, dry, well-ventilated warehouse away from direct sunlight, strong oxidizers, and strong alkalis. Under optimal storage conditions, the shelf life is 24 to 36 months.
Q4: Can Chinese manufacturers supply custom micronized mesh sizes for specific industrial uses?
Yes. Leading factories such as Gentolex support custom particle size engineering from standard 80 mesh up to 320 fine mesh via jet-milling technologies to satisfy specific solubility rate criteria.
Q5: Is complete documentation provided for customs clearance in America and Europe?
Absolutely. All export orders include a Certificate of Analysis (COA), Safety Data Sheet (SDS / MSDS) compliant with OSHA/GHS, Packing List, Commercial Invoice, and Certificate of Origin (COO). EU REACH documentation is also available upon request.

Gentolex Group Major Products & Supply Chain Capabilities

Our main services focus on supplying peptides APIs and Custom Peptides, FDF license out, Technical Support & Consultation, Product Line and Lab Setup, Sourcing & Supply Chain Solutions.

Chemicals Products

An overall factory construction area of 250,000 square meters under international standard to offer flexible, scalable and cost-effective solutions.

Pharmaceutical Ingredients

Gentolex offers an extensive range of APIs and intermediates for development study and commercial application with cGMP standard from long-term collaborations. Documents and Certificates are supported to customers worldwide.

Development

Comprehensive R&D technical support, custom synthesis scale-up, and chemical formulation optimization services tailored to enterprise requirements.

Procurement Service

For those clients who prefer to avoid the complexity of dealing with multiple points of contact, we provide extra customized procurement services with the most superior and comprehensive supply chain sources.

About Gentolex

Gentolex’s goal is to create opportunities connecting the world with better services and guaranteed products. Up to date, Gentolex Group has been serving customers from more than 10 countries, specially, representatives are established in Mexico and South Africa. Our main services focus on supplying peptides APIs and Custom Peptides, FDF license out, Technical Support & Consultation, Product Line and Lab Setup, Sourcing & Supply Chain Solutions.

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