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Comprehensive technical breakdown of CAS 6358-07-2, structural properties, synthesis metrics, quality verification protocols, and global compliance parameters.
2-Amino-6-Chloro-4-Nitrophenol (CAS: 6358-07-2) is a specialized substituted aromatic derivative comprising an ortho-aminophenol core with electro-negative chlorine and nitro functional groups. This precise spatial arrangement grants the compound unique electronic properties, making it an indispensable intermediate in hair coloration chemistry, specialized dye synthesis, energetic material research, and active pharmaceutical ingredient (API) building blocks.
| Technical Parameter | Standard Specification | Testing Methodology / Analytical Instrument |
|---|---|---|
| Chemical Name | 2-Amino-6-chloro-4-nitrophenol | IUPAC Nomenclature |
| CAS Registry Number | 6358-07-2 | CAS Database Index |
| Molecular Formula | C₆H₅ClN₂O₃ | Mass Spectrometry (MS) Verification |
| Assay / Chemical Purity | ≥ 99.0% (Custom grades up to 99.5%) | High-Performance Liquid Chromatography (HPLC) |
| Physical Appearance | Yellow to brownish crystalline powder | Visual / Colorimetric Inspection |
| Melting Point Range | 165.0 °C - 170.0 °C | Automated Melting Point Apparatus |
| Loss on Drying (LOD) | ≤ 0.50% | Thermogravimetric Analysis (TGA) / Vacuum Oven |
| Heavy Metal Impurities | ≤ 10 ppm total | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) |
| Solubility Profile | Soluble in ethanol, acetone, and ethyl acetate; sparingly soluble in water | Standard Solvent Solubility Matrix Test |
Our industrial production of 2-Amino-6-Chloro-4-Nitrophenol utilizes a streamlined, low-carbon nitration and selective reduction pathway designed to yield ultra-pure target compounds while minimizing environmentally hazardous by-products.
The standard synthetic route initiates via controlled chlorination of 4-nitrophenol, followed by regional nitration and step-wise chemical reduction. Precision control over reaction temperatures, pH buffers, and catalytic hydrogenation ensures that isomeric impurities—such as 4-amino-2-chloro-6-nitrophenol or unreacted 2-chloro-4-nitrophenol—are maintained below stringent regulatory thresholds (< 0.10%).
Serves as a crucial oxidative hair dye precursor. It reacts with developer oxidants to form resilient, long-lasting color chromophores with exceptional light-fastness and wash-resistance, fully compliant with global cosmetic safety frameworks.
Utilized in structural drug design as a versatile functionalized aromatic intermediate. The ortho-amino-hydroxy motif provides an ideal template for heterocycle synthesis (e.g., benzoxazoles) in antimicrobial research.
Acts as an essential precursor for active crop protection compounds, selective herbicides, and specialized industrial indicators requiring rigid structural stability under diverse pH conditions.
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Our centralized manufacturing complexes in China operate under strict international standard guidelines. Vertical integration of raw chemical precursors ensures uninterrupted raw material feeds, mitigating global market volatility and delivering scalable multi-ton commercial capacities.
We strictly adhere to ESG (Environmental, Social, and Governance) principles. Our advanced waste-water treatment facilities, continuous solvent recovery systems, and hazardous material management systems meet EU REACH, US TSCA, and regional environmental standards.
To eliminate procurement complexities, Gentolex Group maintains local customer support teams and established regional hubs across strategic international markets, including dedicated representatives in Mexico and South Africa. This localized framework ensures immediate technical consultation, real-time tracking, seamless customs clearance, and tailored inventory buffering for global enterprises.
We provide versatile packaging configurations—ranging from 25 kg fiber drums with double PE inner liners to multi-ton UN-approved ISOTANK containers for liquid precursors—guaranteeing product integrity across sea, air, and overland intermodal transit.
Gentolex’s goal is to create opportunities connecting the world with better services and guaranteed products. Up to date, Gentolex Group has been serving customers from more than 10 countries, specially, representatives are established in Mexico and South Africa.
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