High-purity chemical APIs, peptides, and customized industrial solutions delivered under strict international cGMP standards.
An in-depth chemical profile, molecular mechanics, and global industrial manufacturing parameters.
Sodium Thioglycolate (also structurally designated as Sodium Mercaptoacetate; CAS Number: 367-51-1; Molecular Formula: C2H3NaO2S) represents an essential organosulfur compound characterized by its dual functional reactive sites: a nucleophilic thiol (-SH) group and a carboxylate (-COONa) salt moiety.
The strong reducing activity stems from the rapid cleavage and substitution capabilities of the thiolate anion, enabling efficient reduction of disulfide bonds in biological keratin, complexation with heavy metal ions (particularly copper, iron, and molybdenum), and rapid oxidation-reduction balancing in anaerobic diagnostic cultures. As an OEM manufacturer, maintaining exact pH ranges (typically 6.5 to 8.0 for aqueous solutions) and preventing iron contamination is vital to avoid premature degradation or undesirable color transformations (pink/purple complexing).
We provide chemical bulk synthesis tailored to specific technical applications, ranging from high-density mining reagents to ultra-pure cosmetic ingredients.
| Grade | Assay / Concentration | Key Application Focus |
|---|---|---|
| Mining Depressant Grade | 40.0% - 45.0% Liquid Solution | Copper-Molybdenum ore separation flotation |
| Cosmetic Pure Grade | 98.5% - 99.5% Powder / Crystals | Depilatory creams & permanent waving solutions |
| Microbiological Grade | ≥ 99.0% Reagent Grade | Fluid Thioglycolate Medium (FTM) broth |
| Industrial Oilfield Grade | 45.0% Technical Solution | H2S scavenger & high-temp corrosion inhibitor |
Sodium Thioglycolate operates as an indispensable reagent across diverse sectors, including mineral extraction, cosmetics, oilfield chemistry, and life science research.
In the extraction of Molybdenum and Copper, Sodium Thioglycolate serves as an organic, non-toxic depressant for pyrite and chalcopyrite during molybdenite recovery. It serves as a direct alternative to toxic inorganic depressants like Sodium Cyanide (NaCN) and Sodium Sulfide (Na2S), drastically reducing hazardous chemical footprint and lowering industrial wastewater remediation costs.
Within cosmetic chemistry, Sodium Thioglycolate acts as a principal reductant in hair waving lotions and depilatory creams. By reducing cysteine disulfide (-S-S-) bridges in human keratin to free thiol groups (-SH), it enables hair structural reshaping or dissolution. OEM formulations require strict odor-masking optimization and precise trace-metal reduction to avoid skin irritation.
In high-temperature oil wells, Sodium Thioglycolate is formulated into specialized downhole corrosion inhibitors and hydrogen sulfide (H2S) scavengers. Its iron-chelating properties mitigate ferric sulfide scale buildup on drill strings and pipeline networks, maintaining asset integrity under severe hydrothermal stress.
Built upon scalable international manufacturing standards, delivering consistent purity, safety, and operational reliability.
Gentolex’s goal is to create opportunities connecting the world with better services and guaranteed products. Up to date, Gentolex Group has been serving customers from more than 10 countries, specially, representatives are established in Mexico and South Africa. Our main services focus on supplying peptides APIs and Custom Peptides, FDF license out, Technical Support & Consultation, Product Line and Lab Setup, Sourcing & Supply Chain Solutions.
An overall factory construction area of 250,000 square meters under international standard allows us to offer flexible, scalable, and cost-effective solutions. Gentolex offers an extensive range of APIs and intermediates for development study and commercial application with cGMP standard from long-term collaborations. Full documentation and certificates are supported to customers worldwide.
How we achieve industrial consistency, low heavy-metal limits, and optimized solution stability.
Industrial synthesis of Sodium Thioglycolate is primarily conducted via the reaction between Sodium Chloroacetate and Sodium Hydrosulfide (NaHS) or thiourea in an aqueous alkaline environment:
To prevent side-reactions such as the formation of thiodiglycolic acid or dithiodiglycolic acid, our state-of-the-art facilities execute automatic temperature control (<45°C), nitrogen gas blanket purging, and continuous stoichiometric monitoring during hydrogen sulfide addition.
Every OEM batch undergoes rigorous batch-testing before dispatch, adhering to strict ISO 9001 quality management protocols. Our analytical testing package includes:
Navigating international regulatory frameworks and sustainable chemical processing demands.
Global mining operations face increasing environmental pressures to eliminate toxic cyanide compounds. Sodium Thioglycolate provides a high-selectivity, eco-friendly option for copper-moly separation, accelerating green mining transformation across North America, Chile, and Australia.
For European and American buyers, regulatory compliance is paramount. Gentolex maintains full EU REACH documentation, SDS compliance under GHS Rev. 8, and ISO 14001 environmental safety certifications for smooth international customs clearance.
For clients preferring to avoid managing multiple supply chain points, Gentolex provides specialized procurement services with end-to-end customized packaging, drum filling, IBC tote stabilization, and direct-to-port logistics management.
Stay updated with our latest scientific advancements, API synthesis developments, and supply chain insights.
Addressing commercial procurement, storage parameters, chemical safety, and OEM manufacturing queries.










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